 |
| |
Etudes
en cours |
|
|
|
|
In
part because most studies in Asia have found low Hib
disease incidence, few Asian countries use Hib vaccine
in routine immunization programs.
It is unclear if Hib is truly rare in Asia or if unmeasured
disease exists. |
|
| |
Justification/contexte de l’étude |
In part because most studies in Asia have found low Hib
disease incidence, few Asian countries use Hib vaccine in
routine immunization programs. It is unclear if Hib is truly
rare in Asia or if unmeasured disease exists.
|
| |
| |
Objectifs |
|
To determine the proportion
of pneumonia and meningitis outcomes due
to Hib using Hib conjugate vaccine as a probe.
|
| |
Type d’étude |
|
Modified case control design
with vaccine distributed randomly and cases and controls
identified from hospitals and the community.
|
| |
Population
|
|
Children < 2 years of
age living in Dhaka, Bangladesh.
|
| |
Taille d’échantillon |
|
68,000 children given either
Hib-DPT vaccine or DPT alone.
|
| |
Résultats attendus / définition
de cas |
|
Primary outcome : Radiologically
proven pneumonia based on the WHO trialists definition
Secondary outcomes: Various other pneumonia and meningitis
outcomes
|
| |
Date du premier recrutement |
|
|
| |
Institutions collaboratrices |
|
International Center for
Diarrheal Disease Research, Bangladesh
Johns Hopkins University
|
| |
Financement
de l’étude |
|
Asian Development Bank
Aventis Pasteur
|
| |
Etat d’avancement |
|
|
| |
| - Protocole rédigé |
|
Yes |
| - Premier sujet inclus |
|
Yes |
| - Inclusion achevée |
|
Yes |
| - Analyse achevée |
|
No |
| - Article rédigé
|
|
No |
| - Article accepté |
|
No |
|
| |
Résultats |
|
Results embargoed as of
May 2004
|
|
| |
|
|
